ABSTRACT

Examination of crude methanol extracts of four Sudanese plants (Azadirachta indica, Acacia nilotica, Balanites aegyptiaca and Allium sativa) revealed that only three species had a considerable in-vitro anti-leishmanial activity on Leishmania major promastigotes. The plants Azadrachta indica, Allium sativa, and Acacia nilotica gave a LC50 of 10.2, 4.94, and 89.38 μg/ml, respectively. Extracts of Balanites aegyptiaca had a moderate biological activity on L major promastigotes.

Keywords: Leishmaniasis, cutaneous, herbal therapy, in vitro