Laboratory Results of Cystic Echinococcosis in 2017 and 2018
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Original Investigation
P: 207-210
September 2021

Laboratory Results of Cystic Echinococcosis in 2017 and 2018

Turkiye Parazitol Derg 2021;45(3):207-210
1. Bursa Uludağ Üniversitesi Tıp Fakültesi, Mikrobiyoloji Anabilim Dalı, Bursa, Türkiye
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No information available
Received Date: 08.03.2021
Accepted Date: 15.04.2021
Publish Date: 04.08.2021
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ABSTRACT

Objective:

This study aimed to retrospectively examine the indirect haemagglutination (IHA) test results of patients suspected of cystic echinococcosis (CE) and admitted to Bursa Uludağ University Health Practice and Research Center Hospital.

Methods:

Serum samples in the serology laboratory of our hospital were evaluated using the commercial Cellognost® echinococcosis IHA (Siemens Healthcare Diagnostics, Marburg, Germany) test based on the manufacturer's recommendations. In the IHA test, ≥1:64 serum titres were accepted as positive.

Results:

Seropositivity was determined in 213 (19.9%) of 1.072 patients suspected of having CE by the IHA method. Of the patients with seropositivity, 120 (56.3%) were female and 93 (43.7%) were male. The highest positivity rate in both sexes was found in patients aged 20-29 years (22.5% in women; 14.1% in men).

Conclusion:

The results indicate that CE maintains its importance as a public health problem in Bursa as in Turkey.

Keywords: Cystic echinococcosis, IHA, Bursa, Turkey

References

1
Brunetti E, Kern P, Vuitton DA; Writing Panel for the WHO-IWGE. Expert consensus for the diagnosis and treatment of cystic and alveolar echinococcosis in humans. Acta Trop 2010; 114: 1-16. 
2
Işıtmangil T, Görür R, Yiğit N, Erdik O, Yıldızhan A,Fatih C. Evaluation of 308 cases patient surgically treated for thoracic hydatidosis. Turkish J Thorac and Cardiovasc Surg 2010; 18: 27-33.
3
Budke CM, White AC Jr, Garcia HH. Zoonotic larval cestode infections: neglected, neglected tropical diseases? PLoS Negl Trop Dis 2009; 3: e319.
4
Bhutani N, Kajal P. Hepatic echinococcosis: A review. Ann Med Surg (Lond) 2018; 36: 99-105. 
5
Junghanss T, da Silva AM, Horton J, Chiodini PL, Brunetti E. Clinical management of cystic echinococcosis: state of the art, problems, and perspectives. Am J Trop Med Hyg 2008; 79: 301-11. 
6
Belhassen-García M, Romero-Alegria A, Velasco-Tirado V, Alonso-Sardón M, Lopez-Bernus A, Alvela-Suarez L, et al. Study of hydatidosis-attributed mortality in endemic area. PLoS One 2014; 9: e91342. 
7
Cherradi Y, Afifi R, Khannoussi W, Firwana M, Rahaoui A, Benazzouz M et al. Long-term results of percutaneous management of liver hydatid cysts: Experience of university hospital in endemic region. J Med Sur Res 2016; 3: 275-81.
8
Siles-Lucas M, Casulli A, Conraths FJ, Müller N. Laboratory Diagnosis of Echinococcus spp. in Human Patients and Infected Animals. Adv Parasitol 2017; 96: 159-257. 
9
Altıntaş N, Yazar S. Cystic Echinococcosisde İmmun Tanı. Echinococcosis. Editörler: Altıntaş N, Tınar R, Çoker A. Hidatidoloji Derneği Yayınları, İzmir 2004: 159-180.
10
Biava MF, Dao A, Fortier B. Laboratory diagnosis of cystic hydatic disease. World J Surg 2001; 25: 10-4. 
11
Agudelo Higuita NI, Brunetti E, McCloskey C. Cystic Echinococcosis. J Clin Microbiol 2016; 54: 518-23. 
12
Yılmaz GR, Babür C. Diagnosis of Echinococcosis. Turk Hij Den Biyol Derg 2007; 64: 35-44.
13
Jin Y, Anvarov K, Khajibaev A, Hong S, Hong ST. Serodiagnosis of echinococcosis by ELISA using cystic fluid from Uzbekistan sheep. Korean J Parasitol 2013; 51: 313-7.
14
Chirag S, Fomda BA, Khan A, Malik AA, Lone GN, Khan BA, et al. Detection of hydatid-specific antibodies in the serum and urine for the diagnosis of cystic echinococcosis in patients from the Kashmir Valley, India. J Helminthol 2015; 89: 232-7. 
15
Aksoy U, Inci A. Kistik ekinokokkozisin serolojik tanisinda in-house enzim immün yöntemi ve indirek hemaglütinasyon yönteminin, kullanilmasi [Application of in-house enzyme immunoassay and indirect hemagglutination methods for the serologic diagnosis of cystic echinococcosis]. Mikrobiyol Bul 2004; 38: 245-51. 
16
Kiliç S, Babür C, Taylan Ozkan A. Kist hidatik ön tanili olgularda indirek hemaglütnasyon ve ELISA yöntemleri ile alinan sonuçlarin karşilaştirilmasi [Comparison of the results of indirect hemagglutination and ELISA methods for the cases prediagnosed as hydatid cyst disease]. Mikrobiyol Bul 2007; 41: 571-7. 
17
Ammann RW, Eckert J. Cestodes. Echinococcus. Gastroenterol Clin North Am 1996; 25: 655-89. 
18
Gam AA, Neva FA, Krotoski WA. Comparative sensitivity and specificity of ELISA and IHA for serodiagnosis of strongyloidiasis with larval antigens. Am J Trop Med Hyg 1987; 37: 157-61. 
19
Kuru C, Baysal B. Uniloküler kistik ekinokokkozis tanısında indirekt hemaglütinasyon yönteminin değeri. T Parazitol Derg 1999; 23: 251-4.
20
Aslan M, Polat E, Aygün G, Sağlam GM, Kocazeybek B, Atlas K. Kistik ekinokokkozis şüpheli serum örneklerinde IHA, ELISA IgG ve kendi hazırladığımız ELISA IgG test sonuçlarının karşılaştırılması. T Parazitol Derg 2003; 27: 122-4.
21
Çiftçi N, Ateş F, Dağı HT, Fındık D. Kistik ekinokokkoz ön tanısı alan hastaların seropozitifliklerinin değerlendirilmesi. Genel Tıp Derg 2017; 27: 91-4.
22
Tüzemen NÜ, Alver O, Özakın C, Ener B. Kistik ekinokokkozis şüpheli olguların serumlarından 2008-2016 yılları arasında çalışılan İndirekt Hemaglutinasyon sonuçlarının retrospektif olarak değerlendirilmesi. 20. Ulusal Parazitoloji Kongresi Uluslararası Katılımlı, 25-29 Eylül 2017, Eskişehir, s. 605-606, P115.
23
Öztürk R, Midilli K, Aygün G, Eroğlu C, Dirican A, Aslan M, et al. Yabancı ülkelerden ithal edilen pahalı ELISA ve immünofloresan antijenlerinin yerli olanaklarla ucuz olarak elde edilmesi. Flora 1999; 4: 229-310.
24
Yazar S, Yaman O, Cetinkaya F, Sahin I. Cystic echinococcosis in Central Anatolia, Turkey. Saudi Med J 2006; 27: 205-9.
25
Çetinkaya Ü, Hamamcı B, Kaya M, Gücüyetmez S, Kuk S, ve ark. Kistik ekinokkozis ön tanılı hastalarda anti-echinoccus granulosus antikorlarının araştırılması. Turkiye Parazitol Derg 2012; 36: 57-70.
26
Yazar S. Cystic echinococcosis in Kayseri during the last six years.Turkiye Parazitol Derg 2005; 29: 241-3.
27
Hakverdi S, Sayar H, Yaldiz M, Erdoğan S, Akansu B, Canda MS. Cukurova Yöresinde Seyrek Yerleşimli Ekinokokkozis (134 olgu) [Unusual localization of echinococcosis in Cukurova (134 cases)]. Turkiye Parazitol Derg 2009; 33: 77-81.
28
Karaman U, Mıman O, Kara M, Gicik Y, Aycan OM, Atambay M. Kars bölgesinde hidatik kist prevalansı [Hydatid cyst prevalence in the region of Kars.]. Turkiye Parazitol Derg 2005; 29: 238-40. 
29
Delibaş SB, Ozkoç S, Sahin S, Aksoy U, Akisü C. Dokuz Eylül Universitesi Tip Fakültesi Parazitoloji Anabilim Dali Seroloji Laboratuvari’na Kistik Ekinokokkozis şüphesiyle başvuran hastalarin değerlendirilmesi [Evaluation of patients presenting with a suspicion of cystic echinococcosis to the serology laboratory of the Parasitology Department of Dokuz Eylül University Medical Faculty]. Turkiye Parazitol Derg 2006; 30: 279-81.
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