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E-ISSN: 2146-3077
In vitro Assessment of Anti - Cutaneous Leishmaniasis Activity of Some Sudanese Plants
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Original Investigation
VOLUME: 29 ISSUE: 1
P: 3-6
March 2005

In vitro Assessment of Anti - Cutaneous Leishmaniasis Activity of Some Sudanese Plants

Turkiye Parazitol Derg 2005;29(1):3-6
Fatima, A. KHALID 1
Nazar, M. ABDALLA 1
Husam Eldin O. MOHOMED 2
Abdalla M. TOUM 3
Mubark M. A. MAGZOUB 4
M. Siddig ALİ 5
1. Institute of Nuclear Medicine, Molecular Biology and Oncology,University of Gezera, Sudan
2. Department of Pathology, Faculty of Technology, Omdurman, Sudan
3. Faculty of Dermatology, Faculty of Medicine, University of Gezera, Sudan
4. Ministry of Education and Scientific Research, Khartoum, Sudan
5. Department of Medicine, Faculty of Medicine, Khartoum, Sudan
No information available.
No information available
Received Date: 07.10.2003
Accepted Date: 10.02.2005
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ABSTRACT

Examination of crude methanol extracts of four Sudanese plants (Azadirachta indica, Acacia nilotica, Balanites aegyptiaca and Allium sativa) revealed that only three species had a considerable in-vitro anti-leishmanial activity on Leishmania major promastigotes. The plants Azadrachta indica, Allium sativa, and Acacia nilotica gave a LC50 of 10.2, 4.94, and 89.38 μg/ml, respectively. Extracts of Balanites aegyptiaca had a moderate biological activity on L major promastigotes.

Keywords:
Leishmaniasis, cutaneous, herbal therapy, in vitro