ABSTRACT

Objective:

This study was conducted to investigate the frequency of intestinal parasites in substance abusers and to reveal its significance.

Methods:

The study was conducted in Van Yüzüncü Yıl University Medical Faculty Parasitology Research Laboratory and University of Health Sciences Turkey Van Training and Research Hospital between May 2019 and February 2020. The patient group included 150 patients with substance abuse who applied to the Alcohol and Drug Addicted Treatment Center of University of Health Sciences Turkey Van Training and Research Hospital, while the control group included 75 patients who had no chronic illness and did not use cigarettes, alcohol, or drugs. Stool samples were examined using native-Lugol and modified acid-fast staining methods.

Results:

In this study, one or more intestinal parasites were found in 21.3% of 150 patients who applied to the internal medicine outpatient clinic and had no chronic illness and did not use cigarettes, alcohol, or drugs. There was a statistically significant difference between the two groups in terms of the parasite frequency (p=0.03). In the patient group, Giardia intestinalis was detected in 7.3% (p=0.02), Blastocystis hominis in 6.7%, and Hymenolepis nana in 0.7%. Considering the frequency of parasites in terms of age groups, intestinal parasites were found at a higher rate in the 35 and younger age group (23.8%) than in the 36 and older age group (17.2%). Intestinal parasite positivity was found at the highest rate (23.8%) in those using methamphetamine. Constipation (79.3%) was the most prevalent in parasite-positive substance abusers, followed by diarrhea (23%).

Conclusion:

This study contributed to the literature by determining the frequency of intestinal parasites in people addicted to substance, and it was revealed that intestinal parasite infections are a negative consequence of substance addiction. Conclusively, our findings revealed that intestinal parasites should be considered in substance abusers. Also, more detailed studies involving more individuals should be conducted to obtain information about intestinal parasite infections.

Keywords: Substance abusers, intestinal parasites, prevalence

References

Fayer R, Ungar BL. Cryptosporidium spp. and cryptosporidiosis. Microbiol Rev 1986; 50: 458-83.

Abd El Bagi ME, Sammak BM, Mohamed AE, Al Karawi MA, Al Shahed M, Al Thagafi MA. Gastrointestinal parasite infestation. Eur Radiol 2004; 14(Suppl 3): E116-31.

Özcel MA, Özbel Y, Ak M. Özcel’in Tıbbi Parazit Hastalıkları. İzmir: Meta Basım; 2007.

Özcel MA, İnci A, Turgay N, Köroğlu E. Tıbbi ve Veteriner İmmunoparazitoloji. İzmir: Meta Basım; 2007.

Unat EK, Yücel A, Altaş K, Samastı M. Unat’ın Tıp Parazitolojisi. Cerrahpaşa Tıp Fak. Vakfı Yayınları; 1995.

Chen X, Ye M, Zhou YH, Liu FL, Duo L, Li H, et al. High seroprevalence of Toxoplasma gondii and HIV-1 co-infection among drug users in Yunnan province, Southwest China. Sci China Life Sci 2016; 59: 857-9.

Teixeira MC, Pacheco FT, Souza JN, Silva ML, Inês EJ, Soares NM. Strongyloides stercoralis infection in alcoholic patients. Biomed Res Int 2016; 2016: 4872473.

Akgül Ö, Kart Yaşar K, Sapmaz B, Kırkoyun Uysal H, Yıldırmak T, Şimşek F, ve ark. İzlemdeki HIV/AIDS olgularındaki intestinal parazitlerin konvansiyonel ve moleküler yöntemler ile saptanması. Mikrobiyol Bul 2018; 52: 273-83.

Khan W, Khan NI, Bukhari SNF, Begum N. Prevalence of intestinal parasitic infection among drug addicts in district Swat, Khyber Pakhtunkhwa, Pakistan. Iran J Parasitol 2019; 14: 359-61.

Kamel AG, Maning N, Arulmainathan S, Murad S, Nasuruddin A, Lai KP. Cryptosporidiosis among HIV positive intravenous drug users in Malaysia. Southeast Asian J Trop Med Public Health 1994; 25: 650-3.

Libonore M, Bicocchi R, Sighinolfi L, Ghinelli F. Blastocystosis in drug-addicts with HIV-1 infection. Eur J Epidemiol 1990; 6: 108-9.

Frequency of Intestinal Parasites in Substance Abusers

ABSTRACT

References