A Study of Sister Chromatid Exchange (SCE) in Patients with Liver Cystic Hydatid Disease Who Have Been Treated with Albendazole
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Original Investigation
VOLUME: 29 ISSUE: 4
P: 235 - 237
December 2005

A Study of Sister Chromatid Exchange (SCE) in Patients with Liver Cystic Hydatid Disease Who Have Been Treated with Albendazole

Turkiye Parazitol Derg 2005;29(4):235-237
1. Celal Bayar Üniversitesi Tip Fakültesi Tibbi Biyoloji ve Genetik Anabilim Dali, Manisa
2. Atatürk Egitim ve Arastirma Hastanesi Genel Cerrahi Anabilim Dali, Izmir
3. Atatürk Egitim ve Arastirma Hastanesi Mikrobiyoloji Anabilim Dali, Izmir
4. Ege Üniversitesi Tip Fakültesi Parazitoloji Anabilim Dali, Izmir
No information available.
No information available
Received Date: 14.03.2005
Accepted Date: 28.03.2005
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ABSTRACT

A total of 21 patients including 13 females and 8 males who presented at the Microbiology and General Surgery Departments of the Atatürk Research and Training Hospital with complaints of liver cystic hydatid disease have been included in this study. Albendazole was administered to these cystic hydatid patients before and after surgery. The aim of this study was to investigate the probable genotoxic effects of albendazole. SCE testing was applied to the blood samples taken from patients after the treatment and the mutagenic effect of albendazole was investigated by comparison with the control group. Student t - test was used for the statistical analysis of the results.

Keywords:
Genotoxic, albendazole, SCE, cystic hydatid