Öz
Amaç
Bu çalışmanın amacı, bir rehabilitasyon merkezine devam eden engelli hastalarda intestinal protozoonlarınsıklığını belirleyerek intestinal protozoonların engelli bireylerdeki önemini ortaya koymaktır.
Yöntemler
Çalışmaya, 200 engelli hasta ve 100 engelsiz birey olmak üzere toplam 300 kişi dahil edildi. Çalışmaya dahil edilen tüm bireylerden dışkı örnekleri alınarak, nativ-Lugol ve modifiye asit fast yöntemleriyle incelendi.
Bulgular
Çalışmada, engelli bireylerin %41’inde ve kontrol grubundaki bireylerin %9’unda bir ya da daha fazla intestinal protozoon saptandı (p=0,001). Hastaların %18’inde Blastocystis, %15’inde Cryptosporidium spp., %9’unda Giardia intestinalis, %5’inde Cyclospora cayetanensis ve %4’ünde Entamoeba coli saptandı. Hasta alt gruplarından spina bifida hastalarının %83,3’ünde intestinal protozoon bulunurken diğer gruplardaki oranlar daha düşük bulundu. Ayrıca engelli bireylerde protozoon varlığı ile ishal, kabızlık ve iştahsızlık arasında anlamlı bir ilişki olduğu belirlendi (p<0,05).
Sonuç
Engelli bireylerin, özellikle de spina bifida hastalarının intestinal protozoonlar açısından risk altında olduğu ve bu hastaların özellikle fırsatçı protozoonlar yönünden düzenli olarak taranması gerektiği kanaatine varıldı.
Anahtar Kelimeler: Down sendromu, engelli, intestinal protozoonlar, rehabilitasyon, spina bifida
Kaynakça
Chelkeba L, Mekonnen Z, Alemu Y, Emana D. Epidemiology of intestinal parasitic infections in preschool and school-aged Ethiopian children: a systematic review and meta-analysis. BMC Public Health. 2020; 20: 1-16.
Eyayu T, Kiros T, Workineh L, Sema M, Damtie S, Hailemichael W, et al. Prevalence of intestinal parasitic infections and associated factors among patients attending at Sanja Primary Hospital, Northwest Ethiopia: an institutional-based cross-sectional study. PLoS One. 2021; 16.
Faria CP, Zanini GM, Dias GS, da Silva S, de Freitas MB, Almendra R, et al. Geospatial distribution of intestinal parasitic infections in Rio de Janeiro (Brazil) and its association with social determinants. PLoS Neglect Trop Dis. 2017; 11: e0005445s.
Fitri LE, Candradikusuma D, Setia YD, Wibawa PA, Iskandar A, Winaris N, et al. Diagnostic methods of common intestinal protozoa: current and future immunological and molecular methods. Trop Med Infect Dis. 2022; 7: 253.
Karaman U, Turan A, Depecik F, Gecit I, Ozer A, Karci E, et al. Frequency of intestinal parasites among administrators and workers in sanitary and non-sanitary institutions. Turkiye Parazitol Derg. 2011; 35: 30-3.
Atas AD, Alim A, Atas M, Artan MO. The investigation of intestinal parasites in two primary schools in different social-economic districts of the city of Yozgat, Turkey. Turkiye Parazitol Derg. 2008; 32: 261-5.
Bahar IH, Karaman M, Kirdar S, Yilmaz O, Celiloglu M, Mutlu D. The importance and validity of anti-Toxoplasma gondii IgG, IgM, IgA antibodies and IgG avidity tests in the diagnosis of Toxoplasmosis infection during pregnancy. Turkiye Parazitol Derg. 2005; 29: 76-9.
Kiani H, Haghighi A, Rostami A, Azargashb E, Tabaei SJ, Solgi A, et al. Prevalence, risk factors and symptoms associated to intestinal parasite infections among patients with gastrointestinal disorders in Nahavand, Western Iran. Rev Inst Med Trop Sao Paulo. 2016; 58: 42.
Afshar MJA, Mohebali M, Mohtasebi S, Teimouri A, Sedaghat B, Saberi R. Intestinal parasites among intellectually disabled individuals in Iran: a systematic review and meta-analysis. Gut Pathog. 2021; 13: 28.
Eluane de Luca SM, Pereira A, Castilho VLP, do Nascimento Gonçalves EM, Lallo MA. Infection by intestinal parasites in disabled patients and their guardians. Revista de Ciências Médicas e Biológicas. 2021; 20: 619-23.
Arani AS, Alaghehbandan R, Akhlaghi L, Shahi M, Lari AR. Prevalence of intestinal parasites in a population in south of Tehran, Iran. Rev Inst Med Trop Sao Paulo. 2008; 50: 145-9.
Yula E, Deveci Ö, İnci M, Tekin A. Intestinal parasites and report of etiological analysis in a state hospital. J Clin Exp Invest. 2011; 2: 74-9.
Özcel MA, Özbel Y, Ak M. Özcel'in tıbbi parazit hastalıkları. İzmir: Türkiye Parazitoloji Derneği; 2007.
Kurniawan A, Karyadi T, Dwintasari S, Sari IP, Yunihastuti E, Djauzi S, et al. Intestinal parasitic infections in HIV/AIDS patients presenting with diarrhoea in Jakarta, Indonesia. Trans Roy Soc Trop Med Hyg. 2009; 103: 892-8.
Rasti S, Hassanzadeh M, Hooshyar H, Momen-Heravi M, Mousavi SGA, Abdoli A. Intestinal parasitic infections in different groups of immunocompromised patients in Kashan and Qom cities, central Iran. Scand J Gastroenterol. 2017; 52: 738-41.
Jeske S, Bianchi T, Moura M, Baccega B, Pinto N, Berne M, et al. Intestinal parasites in cancer patients in the South of Brazil. Braz J Biol. 2017; 78: 574-8.
Baiomy AM, Mohamed KA, Ghannam MA, Shahat SA, Al-Saadawy AS. Opportunistic parasitic infections among immunocompromised Egyptian patients. J Egypt Soc Parasitol. 2010; 40: 797-808.
Rodríguez Perón JM, Mora González SR, Acosta Cabrera EB, Menéndez López JR. Índice de masa corporal como indicador en la estratificación del riesgo aterogénico para la vigilancia en salud. Revista Cubana de Medicina Militar. 2004; 33.
Tappeh KH, Mohammadzadeh H, Rahim RN, Barazesh A, Khashaveh S, Taherkhani H. Prevalence of intestinal parasitic infections among mentally disabled children and adults of Urmia, Iran. Iran J Parasitol. 2010; 5: 60-4.
Pakmehr A, Omidian M, Turki H, Fararouei M, Sarkari B. Intestinal parasitic infections among intellectually disabled individuals in Bandar Abbas County, Southern Iran. J Parasitol Res. 2022; 2022: 8406636.
Mohammadi-Meskin V, Hamedi Y, Heydari-Hengami M, Eftekhar E, Shamseddin J, Sharifi-Sarasiabi K. Intestinal parasitic infections in mental retardation center of Bandar Abbas, Southern Iran. Iran J Parasitol. 2019; 14: 318-25.
Shehata AI, Hassanein F. Intestinal parasitic infections among mentally handicapped individuals in Alexandria, Egypt. Ann Parasitol. 2015; 61: 275-81.
Sirivichayakul C, Pojjaroen-anant C, Wisetsing P, Siripanth C, Chanthavanich P, Pengsaa K. Prevalence of intestinal parasitic infection among Thai people with mental handicaps. Southeast Asian J Trop Med Public Health. 2003; 34: 259-63.
Lee J, Park GM, Lee DH, Park SJ, Yong TS. Intestinal parasite infections at an institution for the handicapped in Korea. Korean J Parasitol. 2000; 38: 179-81.
Gatti S, Lopes R, Cevini C, Ijaoba B, Bruno A, Bernuzzi AM, et al. Intestinal parasitic infections in an institution for the mentally retarded. Ann Trop Med Parasitol. 2000; 94: 453-60.
Fentahun AA, Asrat A, Bitew A, Mulat S. Intestinal parasitic infections and associated factors among mentally disabled and non-disabled primary school students, Bahir Dar, Amhara regional state, Ethiopia, 2018: a comparative cross-sectional study. BMC Infect Dis. 2019; 19: 1-12.
Soosaraie M, Pagheh A, Gholami S. Prevalence of intestinal parasitic infections in rehabilitation centers in Golestan Province, Iran. Med Lab J. 2014; 8.
Rhongbutsri P, Saichua P, Navaphongpaveen K, Taylor A, Leelawongtawon R, Kitvatanachai S. Intestinal parasitic infections in students at a school for handicapped children in Khon Kaen Province, Thailand. Thammasat Medical Journal. 2010; 10: 406-10.
de Freitas JT, da Silva Matos J, Scarabeli SC, Fonseca ABM, da Silva Barbosa A, Bastos OMP, et al. Intestinal parasites in children with neurological disorders treated at a rehabilitation institution in Niterói, Rio de Janeiro, Brazil. Revista de Patologia Tropical/Journal of Tropical Pathology. 2017; 46: 171-84.
Seferoğlu O, Karaman Ü, Aldemİr İ, Kolören Z.Giardia intestinalis. ODU Journal of Medicine. 2016; 3: 88-99.
Aydemir S, Afshar M, Şahin M, Cengiz Z, Elasan S, Barlık F, et al. The impact of COVID-19 pandemic on intestinal parasite frequency: a retrospective study. East J Med. 2023; 28: 82-6.
Salehi M, Mardaneh J, Niazkar HR, Minooeianhaghighi M, Arshad E, Soleimani F, et al. Prevalence and subtype analysis ofBlastocystis hominis isolated from patients in the Northeast of Iran. J Parasitol Res. 2021; 2021: 8821885.
Ekici A, Unlu A, Aydemir S, Barlik F, Yilmaz H. Subtyping ofCryptosporidium parvum obtained from humans and calves in Van, Turkey. Iran J Parasitol. 2022; 17: 366-74.
Lima A, Moore S, Barboza Jr M, Soares A, Schleupner M, Newman R, et al. Persistent diarrhea signals a critical period of increased diarrhea burdens and nutritional shortfalls: a prospective cohort study among children in northeastern Brazil. J Infect Dis. 2000; 181: 1643-51.
Cicek M, Yıldırım İH, Cengiz ZT, Karaman Ü. Single-strand conformation polymorphism-based genetic characterization of theCyclosporacayetanensis strains collected from different provinces in Turkey. Ann Agr Env Med. 2021; 28: 267-70.
Ekici A, Unlu AH, Yilmaz H, Cengiz ZTAS, Beyhan YE. Evaluation of nested PCR for diagnosis ofCyclosporacayetanensis in a sample of immunosuppressed and diarrheic patients in Turkey. Parasitol United J. 2021; 14: 141-5.
Jones TP, Hart JD, Kalua K, Bailey RL. A prevalence survey of enteral parasites in preschool children in the Mangochi District of Malawi. BMC Infect Dis. 2019; 19: 838.
Unat K. Unat'ın Tıp Parazitolojisi - İnsanın ökaryonlu parazitleri ve bunlarla oluşan hastalıkları. İstanbul: Cerrahpaşa Tıp Fak.Vakfı Yayınları; 1995.
Haque R, Mondal D, Duggal P, Kabir M, Roy S, Farr BM, et al.Entamoeba histolytica infection in children and protection from subsequent amebiasis. Infect Immun. 2006; 74: 904-9.
Karakuş İ, Taş Cengiz Z, Ekici A. Evaluation of intestinal parasites and some clinical symptoms in children with diarrhea. Turkiye Parazitol Derg. 2022; 46: 39-44. English. Erratum in: Turkiye Parazitol Derg. 2022; 46: 166.
