Öz
Leukositoklastik vaskulitis (LCV), küçük damarları etkileyen ve genellikle enfeksiyonlar, maligniteler, ilaçlar ve otoimmün hastalıklarla ilişkilendirilen bir vaskulit türüdür. Bu vakada, LCV kliniği ile başvuran 75 yaşındaki kadın hastada, yaygın etiyolojik faktörler dışlandıktan sonra kist hidatik hastalığı olası bir neden olarak ortaya çıkmıştır. Bu vaka, LCV’nin ayırıcı tanısında, özellikle bu enfeksiyonların endemik olduğu bölgelerde ve çevresel risk faktörlerine maruz kalan hastalarda, paraziter enfeksiyonların, özellikle kist hidatik hastalığının göz önünde bulundurulmasının önemini vurgulamaktadır.
Anahtar Kelimeler: Kist hidatik, leukositoklastik vaskülitis, paraziter enfeksiyonlar
Kaynakça
Fraticelli P, Benfaremo D, Gabrielli A. Diagnosis and management of leukocytoclastic vasculitis. Intern Emerg Med. 2021; 16: 831-41.
Khetan P, Sethuraman G, Khaitan BK, Sharma VK, Gupta R, Dinda AK, et al. An aetiological & clinicopathological study on cutaneous vasculitis. Indian J Med Res. 2012; 135: 107-13.
Isik S, Sozmen SC, Guzeloglu E, Ozturk T, Asilsoy S. Pulmonary hydatid cyst disease mimicking necrotizing pneumonia in a child with leukocytoclastic vasculitis. Turk Pediatri Ars. 2018; 53: 117-9.
Caproni M, Verdelli A. An update on the nomenclature for cutaneous vasculitis. Curr Opin Rheumatol. 2019; 31: 46-52.
Sunderkotter CH, Zelger B, Chen KR, Requena L, Piette W, Carlson JA, et al. Nomenclature of cutaneous vasculitis: dermatologic addendum to the 2012 Revised International Chapel Hill Consensus Conference nomenclature of vasculitides. Arthritis Rheumatol. 2018; 70: 171-84.
Alpsoy E. Cutaneous vasculitis; an algorithmic approach to diagnosis. Front Med (Lausanne). 2022; 9: 1012554.
Mullick FG, McAllister HA, Wagner BM, Fenoglio JJ. Drug related vasculitis. Clinicopathologic correlations in 30 patients. Hum Pathol. 1979; 10: 313-25.
Corra A, Verdelli A, Mariotti EB, Ruffo di Calabria V, Quintarelli L, Aimo C, et al. Cutaneous vasculitis: lessons from COVID-19 and COVID-19 vaccination. Front Med (Lausanne). 2022; 9: 1013846.
Wen H, Vuitton L, Tuxun T, Li J, Vuitton DA, Zhang W, et al. Echinococcosis: advances in the 21st century. Clin Microbiol Rev. 2019; 32: e00075-18.
Sahin S, Kaya B. Evaluation of Hydatid Cyst Cases: A Single-center retrospective study. Turkiye Parazitol Derg. 2025;48: 222-7.
Govindasamy A, Bhattarai PR, John J. Liver cystic echinococcosis: a parasitic review. Ther Adv Infect Dis. 2023; 10: 20499361231171478.
Nunnari G, Pinzone MR, Gruttadauria S, Celesia BM, Madeddu G, Malaguarnera G, et al. Hepatic echinococcosis: clinical and therapeutic aspects. World J Gastroenterol. 2012; 18: 1448-58.
Bektan Kanat B, Ulugerger Avci G, Icli TB, Doventas A. Concomitant polymyalgia rheumatica and giant Cell Arteritis Associated with Cystic echinococcosis: a rare geriatric case. Acta Parasitol. 2024; 69: 1085-9.
Rigano R, Profumo E, Siracusano A. New perspectives in the immunology ofEchinococcus granulosus infection. Parassitologia. 1997; 39: 275-7.
Rigano R, Profumo E, Teggi A, Siracusano A. Production of IL-5 and IL-6 by peripheral blood mononuclear cells (PBMC) from patients withEchinococcus granulosus infection. Clin Exp Immunol. 1996; 105: 456-9.
Zhang W, Li J, McManus DP. Concepts in immunology and diagnosis of hydatid disease. Clin Microbiol Rev. 2003; 16: 18-36.
Rigano R, Profumo E, Ioppolo S, Notargiacomo S, Ortona E, Teggi A, et al. Immunological markers indicating the effectiveness of pharmacological treatment in human hydatid disease. Clin Exp Immunol. 1995; 102: 281-5.
Aimulajiang K, Guo B. Echinococcosis immune response, immunopathogenesis and immune evasion from the human host. Li J, Wang W, Mehlhorn H, (editors). Echinococcus: control and elimination of echinococcosis with a focus on China and Europe. Springer; 2024. p.109-128.
