Öz
Amaç
Demodeks blefariti, göz kapaklarında, kirpik diplerinde, Zeiss bezlerinde ve Meibomian bezlerinde Demodeks akarlarının aşırı çoğalmasıyla oluşan ve genellikle gözden kaçan yaygın bir göz iltihabı rahatsızlığıdır. Bu çalışmanın amacı klasik Demodeks blefarit tedavisine yanıtsız olgularda ivermektin tablet oral tedavisinin etkinliğini araştırmaktır.
Yöntemler
Çalışmaya kronik semptomatik blefarit tanısı almış toplam 35 hasta (17 erkek ve 18 kadın) dahil edildi.ÇalışmayaÇekirge Devlet Hastanesi ve Bursa Dünyagöz Hastanesi Göz Hastalıkları Klinikleri’ne 12 Aralık 2017 ile 15 Nisan 2021 tarihleri arasındabaşvuran ve klasik Demodeks blefariti tedavisine dirençli Cylindrical dandruff’lu hastalar dahil edildi. Bu olgularda Demodeks klasik tedavisinin ardından 30 gün arayla 0,2 mg/kg’lık iki dozda oral ivermektin başlandı. Klasik Demodeks blefariti tedavisi öncesi ve ivermektin tedavisi sonrası kirpiklerde Demodeks varlığı, oküler yüzey hastalığı indeksi (OSDI) skoru değerlendirildi. Tüm olgulara detaylı biyomikroskopik göz muayenesi yapıldı.
Bulgular
Hastaneye kabul edilen toplam 35 hastanın 17’si (%48,6) erkek [ortalama ± standart sapma (SS): 48,41±15,62, min-maks: 18-75] ve 18’i (%51,4) kadındı (ortalama ± SS: 51,17±14,98, min-maks: 19-73). Erkekler ve kadınlar arasında yaş ortalamaları açısından istatistiksel olarak anlamlı bir fark saptanmadı (p=0,598). Klasik Demodeks blefariti tedavisi öncesi ve oral ivermektin tedavisi sonrası OSDI skorlama ortalama ± SS değerleri sırasıyla 77,47±5,74 ve 6,69±4,71 idi.
Sonuç
Demodeks ilişkili blefarit tedavisinde klasik tedaviye yanıt vermeyen olgularda oral ivermektin kullanımının etkili bir tedavi seçeneği olabileceği kanaatine varıldı.
Anahtar Kelimeler: Demodeks sp., blefarit, oral ivermektin, Bursa, Türkiye
Kaynakça
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