E-ISSN 2146-3077
Original Article
Intestinal Protozoa in Hiv-Infected Patients: A Retrospective Analysis
1 Ege Üniversitesi Tıp Fakültesi, Parazitoloji Anabilim Dalı, İzmir, Türkiye  
2 Ege Üniversitesi Tıp Fakültesi, Enfeksiyon Hastalıkları ve Klinik Mikrobiyoloji Anabilim Dalı, İzmir, Türkiye  
3 Celal Bayar Üniversitesi Tıp Fakültesi, Parazitoloji Anabilim Dalı, Manisa, Türkiye  
Turkiye Parazitol Derg 2018; 42: 187-190
DOI: 10.5152/tpd.2018.5835
Key Words: HIV, intestinal parasitic infection, Cryptosporidium, Cyclospora, Blastocystis
Abstract

Objective: Intestinal parasitic infections are common in immunodeficient patients. In developing countries, the incidence of diarrhea due to parasitic infections in HIV (human immunodeficiency virus)-positive individuals is reported to be over 90%. The present study aimed to investigate the presence of intestinal protozoa in HIV-positive patients with gastrointestinal complaints.

 

Methods: The fecal samples of 65 HIV-positive patients (14 women, 51 men) were included. Clinical data obtained from patients’ files and laboratory results were retrospectively scanned using laboratory information system. Age, sex, parasite positivity, CD4+ count, HIV RNA level, and antiretroviral therapy information were recorded.

 

Results: Fourteen Cryptosporidium spp. (21.5%), 2 Cyclospora spp. (3.1%), 7 Blastocystis spp. (10.8%), and 1 Cryptosporidium spp.+Blastocystis spp. (1.5%) were detected. The median duration of antiretroviral treatment was 3 months and 12 months in patients with and without parasites in fecal samples, respectively. The duration of antiretroviral treatment was significantly higher in non-infected patients (p=0.002). No significant correlations were found between parasite presence and CD4+ T cell counts or HIV RNA levels.

 

Conclusion: Our findings suggest that positive effects of antiretroviral therapy on the immune system of HIV-infected patients reduce the risk of intestinal parasitic infection, and thus, this treatment may play an important role in protection.

 

Cite this article as: Zorbozan O, Quliyeva G, Tunalı V, Özbilgin A, Turgay N, Gökengin AD. Intestinal Protozoa in Hiv-Infected Patients: A Retrospective Analysis. Turkiye Parazitol Derg 2018; 42(3): 187-90.

Key Words
Authors
All
Reviewer's Corner
Survey
AVES | Copyright © 2018 Turkish Parasitology Association | Latest Update: 10.10.2018