E-ISSN 2146-3077
Original Article
Toxoplasma gondii IgG Seroprevalence in Patients with HIV/AIDS
1 Bakırköy Dr. Sadi Konuk Eğitim ve Araştırma Hastanesi, Enfeksiyon Hastalıkları ve Klinik Mikrobiyoloji, İstanbul, Türkiye  
Turkiye Parazitol Derg 2018; 42: 175-179
DOI: 10.5152/tpd.2018.5706
Key Words: HIV/AIDS, Toxoplasma gondii, seropositivity

Objective: Toxoplasmosis is a common opportunistic infection in patients with HIV/AIDS and may cause life-threatening clinical courses, such as encephalitis and pneumonia.


Methods: Patients admitted between January 2006 and August 2017 with anti-HIV positivity confirmed by Western blotting were included in the study. Demographic data, CD4+ T-lymphocyte counts, and Toxoplasma gondii IgG/IgM levels were retrospectively obtained from patient records.


Results: T. gondii IgM positivity was not detected in patients, whereas T. gondii IgG positivity was detected in 267 (43.5%) patients. The T. gondii IgG positivity rate was 37.6% in men who had sex with men (MSM) and 48.4% in heterosexual patients. Furthermore, 42.6% of MSM and 21% of heterosexual patients were university graduates, of which T. gondii IgG positivity was detected in only 33.6% of MSM patients and 42.3% of heterosexual patients.


Conclusion: In our study, high seronegativity was remarkable in MSM patients, particularly those who were highly educated, thus emphasizing the importance of prevention of primary infection in seronegative patients; necessity of prophylaxis in appropriate patients due to encephalitis, which has a high mortality rate and almost always develops after a latent infection; and necessity of screening for toxoplasmosis seropositivity at the time of diagnosis.


Cite this article as: Şenoğlu S, Yeşilbağ Z, Altuntaş Aydın Ö, Kumbasar Karaosmanoğlu H, Kart Yaşar K. Toxoplasma gondii IgG Seroprevalence in Patients with HIV/AIDS. Turkiye Parazitol Derg 2018; 42(3): 175-9.

Key Words
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